Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep1207 | Clinical Cases–Pituitary/Adrenal | ECE2015

Cushing's syndrome secondary to aberrant hormone receptors in a patient with macronodular adrenal hyperplasia ACTH-independent

Vega Maria Molina , Medina Jose Antonio Lopez , Garach Araceli Munoz , Pareja Isabel Cornejo , Perdigones Cristina Diaz , Perez Ana Gomez , Madueno Francisco Tinahones

Introduction: CushingÂ’s syndrome (CS) due to macronodular adrenal hyperplasia ACTH-independent (MAHAI) is rare. Regulation of cortisol secretion by G-protein-coupled receptors (GPCRs) aberrantly expressed is frequently found in MAHAI. Various aberrant receptors have been reported, mostly: GIP, vasopressin, beta-adrenergic, LH/hCG and serotonin.Case report: 61 years old woman. Medical history: type 2 diabetes, hypertension, obesity, dyslipidaemia and...